Elliptocytes present Meaning, Causes, Treatment | Ovalocytes vs Elliptocytes

Elliptocytes Meaning?

Elliptocytes are a particular form of red blood cell that are distinguished by their elliptical or oval shape, which is different from the typical round shape of healthy red blood cells. During a blood smear examination, these aberrant cells can be detected under a microscope. Elliptocytes can vary in size and shape, with both ends pointy or rounded.

Elliptocytes Causes

The presence of elliptocytes can be related to a variety of underlying variables and medical problems. Here are a few typical reasons:

Hereditary Elliptocytosis: 

The elliptocytes in this genetic condition can be inherited from either one or both parents. It may seem as a minor condition or, in rare instances, progress to severe anemia.

Thalassemia: 

Ellipsocytosis may result from some types of thalassemia, a blood condition that affects hemoglobin synthesis.

Iron Deficiency Anemia: 

In some cases, elliptocytes might be produced as a result of iron deficiency.

Liver Disease: 

Eliptocytosis can result from liver conditions including cirrhosis and hepatitis that affect the formation of red blood cells.

Autoimmune Disorders: 

Ellipsocytes may be present as a result of conditions like systemic lupus erythematosus (SLE) and autoimmune hemolytic anemia (AIHA).

Elliptocytes Significance

The presence of elliptocytes can reveal important details about a person's health. These clinical implications are listed below:

Anemia: 

Elliptocytes may be related to anemia, which is characterized by a low hemoglobin or red blood cell count. Weakness, exhaustion, and shortness of breath are some of the signs of anemia.

Anemia hemolytic: 

Hemolytic anemia, which happens when red blood cells are prematurely destroyed, may be experienced by certain people with elliptocytosis. This can cause jaundice, pale complexion, and an enlargement of the spleen.

Complications in Pregnancy: 

Preeclampsia and fetal growth restriction are two issues that may be more common in pregnant people with elliptocytes.

Elliptocytes treatment

The treatment for elliptocytes is determined by the underlying cause as well as the severity of the related symptoms. Here are a few typical methods:

Elliptocytes Treatment or Supportive Care

Treatment for elliptocytosis in moderate cases may concentrate on symptom management and maintaining general health. This involves eating a balanced diet, exercising frequently, and drinking enough water.

Blood Transfusions: 

Periodic blood transfusions may be necessary for people with severe anemia or complications to reduce symptoms and enhance general health.

Medication: 

Immunosuppressants or folic acid supplements may occasionally be administered to treat underlying problems or manage symptoms.

Splenectomy: 

Rarely, a splenectomy (the surgical removal of the spleen) may be advised for people who have significant elliptocytosis-related problems.

Ovalocytes vs. Elliptocytes

Elliptocytes have an elongated or elliptical shape whereas ovalocytes are more rounded and oval-shaped. Elliptocytes can differ significantly in size from typical red blood cells, with some being larger and others being smaller. Ovalocytes, on the other hand, are often larger in size than red blood cells. Elliptocytes are more frequently connected with anemia and hemolytic conditions, whereas ovalocytes are frequently related with genetic problems such as hereditary ovalocytosis or Southeast Asian ovalocytosis.